Mushrooms and the Science of Aging: A Comprehensive Review of Ergothioneine Research
Ergothioneine is a naturally occurring, sulfur-containing amino acid with potent antioxidant properties. It is not synthesized by the human body and must be acquired through dietary intake, primarily from mushrooms, which serve as its principal natural source.
FOXO Transcription Factors and Mushroom-Derived Compounds: A Comprehensive Review of the Longevity Literature
FoxO transcription factors occupy a critical node where cellular stress responses converge with the mechanisms governing longevity. Their signaling pathway architecture and in vitro interactions with fungal constituents are examined.
Pachyman: The Defining Beta-Glucan of Poria cocos
Pachyman is a water-insoluble β‑glucan polysaccharide found in the sclerotium of the basidiomycete fungus *Poria cocos*. Its molecular architecture, the chemical transformations yielding bioactive derivatives, and the body of in vitro pharmacological evidence have been comprehensively surveyed.
